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Our Computational Neuroethology Laboratory is interested in understanding how behaviorally-relevant sensory signals are encoded by cortical neurons, and what factors (e.g. experience, hormones) might lead to plastic changes in that code. We investigate this in the mouse, where ultrasonic communication between animals provides a natural behavioral context for these studies, and transgenic methods offer future possibilities for mechanistic dissection of coding mechanisms. Our experimental approaches include electrophysiology in awake mice, hormonal manipulations, immunohistochemistry, and behavioral analysis. We also employ computational methods to analyze the information processing capabilities of neurons.